Investigational technology Not approved for commercial sale

The Brain-State Vital Sign

The brain has vital signs.
It’s time we could see them.

NVT BVS is an investigational, fully implanted sub-scalp EEG system and BCI-AI platform designed to transform real-world brain activity into longitudinal clinical evidence—beginning with epilepsy.

Epilepsy first Continuous context Clinician accountable

Conceptual visualization. NVT BVS is under development; commercial-system performance remains to be established.

Epilepsy is the first clinical wedge.

Longitudinal brain-state infrastructure is the platform.

The missing signal

Neurology sees snapshots.
Disease happens continuously.

Clinic visitLife between visitsClinic visit
Today’s blind zone

Symptoms, treatment response, sleep and brain-state change unfold beyond the exam room.

For episodic neurological disease, the most important evidence is often the evidence no one sees.

  • 01
    Patients remember imperfectly.

    Diaries are burdensome and events may be missed or misclassified.

  • 02
    Providers treat through uncertainty.

    Brief tests cannot represent weeks or months of lived disease.

  • 03
    Payers lack trusted outcomes.

    Utilization data describes cost, but not the brain state that preceded it.

NVT BVS

The missing middle
in brain monitoring.

Designed to combine the signal continuity of an implant with a discreet, monitoring-first experience.

Conceptual placementUnder the scalp. Above the skull.
Hair
Scalp
NVT BVS
Skull
Brain

Illustrative anatomy—not to scale. Final device design, placement and procedure remain subject to clinical and regulatory validation.

Designed to disappear from view

Fully implanted beneath the scalp, with no intended day-to-day visible hardware.

Designed for the long view

Passive, longitudinal capture aims to reveal patterns that episodic testing cannot.

Monitoring first

A minimally invasive position between external wearables and brain-penetrating interfaces.

External

Wearables

Visible hardware and patient-dependent use can limit longitudinal continuity.

Brain-interfacing

Invasive BCIs

High-bandwidth therapeutic or functional interfaces with greater procedural complexity.

Brain-State Operating System

From signal
to intelligence.

NVT is developing an evidence infrastructure that converts continuous brain activity into prioritized, explainable clinical context—without replacing clinical judgment.

01 · CAPTURE

NVT BVS

Longitudinal sub-scalp EEG

02 · INTERPRET

Edge + cloud AI

Quality, events, trends and context

03 · ORGANIZE

Brain-state graph

Patient-specific longitudinal model

04 · ACT

Clinical workspaces

Patient · provider · payer

Human accountable Clinical decisions remain with qualified providers.

Evidence traceable Every alert links back to signal, context and model version.

AI constrained Agents operate within defined permissions and escalation policies.

One signal. Three kinds of value.

Built around the people
who make care work.

01 / PATIENT

Life first.
Monitoring in the background.

NVT BVS is being designed to reduce the daily work of documenting epilepsy while giving your care team a more complete picture of what happens between visits.

  • No intended visible external hardware
  • Passive monitoring by design
  • Simple context capture when it matters
  • Clear escalation to your care team
9:41

TODAY

Good morning, Maya.

Your monitoring is running in the background.

ConnectedNVT BVS
Optional context

Anything you want your care team to know?

Illustrative future workflow—not a released application.

Start narrow. Build deliberately.

Epilepsy first.

Epilepsy offers a high-need, event-driven indication in which objective longitudinal measurement may change how clinicians characterize disease and assess treatment response.

01

Measurable episodes

Electrical events create a direct starting point for a brain-state vital sign.

02

Persistent uncertainty

Clinical decisions often rely on incomplete diaries and short recording windows.

03

Actionable evidence

Longitudinal patterns may support more informed review of therapy and risk.

CAPTUREReal-world EEG
UNDERSTANDPatient-specific patterns
ACTPrioritized clinical review
PROVEOutcomes and access value

Intentional platform handles

One architecture.
Multiple brain states.

Future applications are research concepts—not validated indications or commercial claims.

CLINICAL WEDGE

Epilepsy

Seizure burden · treatment response

RESEARCH PATH

Cognition

Dementia · cognitive change

RESEARCH PATH

Mood

Depression · state dynamics

RESEARCH PATH

Movement

Parkinson’s · motor states

RESEARCH PATH

Sleep

Alertness · architecture

RESEARCH PATH

Pain

Migraine · episodic context

RESEARCH PATH

Recovery

Neuroplasticity · rehabilitation

RESEARCH PATH

Brain injury

Stroke · TBI · concussion

Evidence, clearly staged

Build trust by showing
what is known—and what is next.

NVT’s scientific foundation includes blinded human signal studies and published algorithm work. The complete chronic commercial system still requires prospective clinical and regulatory validation.

PEER-REVIEWED · HUMAN DATA

Sub-scalp signal validation

Blinded analysis comparing sub-scalp recordings with intracranial EEG during clinically observed care.

View on PubMed

PEER-REVIEWED · RETROSPECTIVE

Automated ictal detection

A subject-specific algorithm study examining seizure detection from sub-scalp recordings.

View on PubMed
THE NVT EVIDENCE LADDER

Claims advance only as evidence advances.

  1. 01
    Safety + feasibility

    Implant, healing, explant and sustained-use endpoints

    TO VALIDATE
  2. 02
    Signal + algorithm validity

    Prespecified performance against appropriate reference standards

    FOUNDATION
  3. 03
    Clinical utility + workflow

    Decision impact, review burden and time-to-action

    TO VALIDATE
  4. 04
    Payer + access value

    Utilization, quality-of-life and health-economic outcomes

    TO VALIDATE

Built at the intersection

Neurology.
Neurosurgery.
AI + medtech.

NeuroView Technology brings together clinicians who understand the consequences of missing brain-state information and operators who know how to build regulated healthcare technology.

RK

Ruben Kuzniecky, MD

Co-founder · Neurology

WD

Werner Doyle, MD

Co-founder · Neurosurgery

SP

Steven Pacia, MD

Co-founder · Neurology

DF

Daniel Friedman, MD, MSc

Co-founder · Epilepsy

SV

Scott Verner

Leadership · Medtech

TD

Timir Datta-Chaudhuri, BS, MS, PhD

Technology · Bioelectronics

A clearer view of the brain

Make the invisible
clinically useful.

Connect with NVT as a patient advocate, clinical collaborator or strategic partner.

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